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Axotomy Induces Drp1-Dependent Fragmentation of Axonal Mitochondria

It is well established that CNS axons fail to regenerate, undergo retrograde dieback, and form dystrophic growth cones due to both intrinsic and extrinsic factors. We sought to investigate the role of axonal mitochondria in the axonal response to injury. A viral vector (AAV) containing a mitochondri...

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Detalhes bibliográficos
Publicado no:Front Mol Neurosci
Main Authors: Kedra, Joseph, Lin, Shen, Pacheco, Almudena, Gallo, Gianluca, Smith, George M.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8209475/
https://ncbi.nlm.nih.gov/pubmed/34149354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnmol.2021.668670
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