Wird geladen...

STRUCTURE-BASED DISCOVERY OF A NEW CLASS OF Bcl-x(L) ANTAGONISTS

Apoptosis, or programmed cell death, plays a key role in normal tissue homeostasis ensuring a proper balance between cell production and cell loss. Anti-apoptotic Bcl-2-family proteins are central regulators of the apoptotic pathway and due to their ability to confer tumor resistance to chemotherapy...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Rega, Michele F., Leone, Marilisa, Jung, Dawoon, Cotton, Naomi J.H., Stebbins, John L., Pellecchia, Maurizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2023964/
https://ncbi.nlm.nih.gov/pubmed/17512966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bioorg.2007.03.001
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!