تحميل...
Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes
Alkylation of DNA at the O(6)-position of guanine is one of the most critical events leading to mutation, cancer, and cell death. The enzyme O(6)-methylguanine-DNA methyltransferase repairs O(6)-methylguanine as well as a minor methylated base, O(4)-methylthymine, in DNA. Mouse lines deficient in th...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
The National Academy of Sciences
1998
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20223/ https://ncbi.nlm.nih.gov/pubmed/9560238 |
| الوسوم: |
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