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Induced Synthesis of O(6)‐Methylguanine‐DNA Methyltransferase in Rat Hepatoma Cells Exposed to DNA‐damaging Agents
When the rat hepatoma cell line H4IIE was treated with DNA‐damaging agents such as N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG), ultraviolet light and γ‐rays, the O(6)‐methylguanine‐DNA methyltransferase activity increased 2 to 3 times over the level seen in non‐treated cells. SDS/polyacrylamide gel...
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| Published in: | Jpn J Cancer Res |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Blackwell Publishing Ltd
1992
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5918658/ https://ncbi.nlm.nih.gov/pubmed/1544875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.1992.tb02354.x |
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