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Inhibition of the Mycobacterium tuberculosis enoyl acyl carrier protein reductase InhA by arylamides
InhA, the enoyl acyl carrier protein reductase (ENR) from Mycobacterium tuberculosis, is one of the key enzymes involved in the type II fatty acid biosynthesis pathway of M. tuberculosis. We report here the discovery, through high-throughput screening, of a series of arylamides as a novel class of p...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2020492/ https://ncbi.nlm.nih.gov/pubmed/17723305 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.08.013 |
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