Defective DNA base excision repair in brain from individuals with Alzheimer's disease and amnestic mild cognitive impairment

Oxidative stress is thought to play a role in the pathogenesis of Alzheimer's disease (AD) and increased oxidative DNA damage has been observed in brain tissue from AD patients. Base excision repair (BER) is the primary DNA repair pathway for small base modifications such as alkylation, deamina...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Weissman, Lior, Jo, Dong-Gyu, Sørensen, Martin M., de Souza-Pinto, Nadja C., Markesbery, William R., Mattson, Mark P., Bohr, Vilhelm A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2007
Gaiak:
Molecular Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018628/
https://ncbi.nlm.nih.gov/pubmed/17704129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm605
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