Expression, Purification, Assay, and Crystal Structure of Perdeuterated Human Arginase I,

Arginase is a manganese metalloenzyme that catalyzes the hydrolysis of L-arginine to yield L-ornithine and urea. In order to establish a foundation for future neutron diffraction studies that will provide conclusive structural information regarding proton/deuteron positions in enzyme-inhibitor compl...

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Bibliographic Details
Main Authors: Di Costanzo, Luigi, Moulin, Martine, Haertlein, Michael, Meilleur, Flora, Christianson, David W.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2018606/
https://ncbi.nlm.nih.gov/pubmed/17562323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2007.04.036
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