In vivo (13)C NMR measurements of cerebral glutamine synthesis as evidence for glutamate–glutamine cycling

The cerebral tricarboxylic acid (TCA) cycle rate and the rate of glutamine synthesis were measured in rats in vivo under normal physiological and hyperammonemic conditions using (13)C NMR spectroscopy. In the hyperammonemic animals, blood ammonia levels were raised from control values of ≈0.05 mM to...

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Bibliografiska uppgifter
Huvudupphovsmän: Sibson, N. R., Dhankhar, A., Mason, G. F., Behar, K. L., Rothman, D. L., Shulman, R. G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences of the USA 1997
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC20152/
https://ncbi.nlm.nih.gov/pubmed/9122259
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