The contribution of GABA to glutamate/glutamine cycling and energy metabolism in the rat cortex in vivo

Previous studies have shown that the glutamate/glutamine (Glu/Gln) neurotransmitter cycle and neuronal glucose oxidation are proportional (1:1), with increasing neuronal activity above isoelectricity. GABA, a product of Glu metabolism, is synthesized from astroglial Gln and contributes to total Glu/...

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Bibliographic Details
Main Authors: Patel, Anant B., de Graaf, Robin A., Mason, Graeme F., Rothman, Douglas L., Shulman, Robert G., Behar, Kevin L.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2005
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC556230/
https://ncbi.nlm.nih.gov/pubmed/15809416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501703102
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