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Determination of the glutamate–glutamine cycling flux using two-compartment dynamic metabolic modeling is sensitive to astroglial dilution

Over the last decade (13)C magnetic resonance spectroscopy ((13)C MRS) combined with the infusion of [1-(13)C]glucose has been used to measure the cerebral rate of the glutamate–glutamine cycle (V(cyc)). However, the effect of the astroglial label dilution pathways on the accuracy and precision of t...

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Detalhes bibliográficos
Main Authors: Shen, Jun, Rothman, Douglas L, Behar, Kevin L, Xu, Su
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613170/
https://ncbi.nlm.nih.gov/pubmed/18766194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2008.102
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