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Glutamine-Glutamate Cycle Flux Is Similar in Cultured Astrocytes and Brain and Both Glutamate Production and Oxidation Are Mainly Catalyzed by Aspartate Aminotransferase

The glutamine-glutamate cycle provides neurons with astrocyte-generated glutamate/γ-aminobutyric acid (GABA) and oxidizes glutamate in astrocytes, and it returns released transmitter glutamate/GABA to neurons after astrocytic uptake. This review deals primarily with the glutamate/GABA generation/oxi...

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Detalhes bibliográficos
Publicado no:Biology (Basel)
Main Authors: Hertz, Leif, Rothman, Douglas L
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372010/
https://ncbi.nlm.nih.gov/pubmed/28245547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biology6010017
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