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Effects of GAT1 Inhibition by Tiagabine on Brain Glutamate and GABA Metabolism in the Anesthetized Rat In Vivo

GABA clearance from the extracellular space after release from neurons involves reuptake into terminals and astrocytes through GABA transporters. The relative flows through these two pathways for GABA released from neurons remains unclear. In this study we determined the effect of tiagabine, a selec...

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Detalhes bibliográficos
Publicado no:J Neurosci Res
Main Authors: Patel, Anant B., de Graaf, Robin A., Rothman, Douglas L., Behar, Kevin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4441585/
https://ncbi.nlm.nih.gov/pubmed/25663257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.23548
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