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Evaluation of cerebral acetate transport and metabolic rates in the rat brain in vivo using (1)H-[(13)C]-NMR

Acetate is a well-known astrocyte-specific substrate that has been used extensively to probe astrocytic function in vitro and in vivo. Analysis of amino acid turnover curves from (13)C-acetate has been limited mainly for estimation of first-order rate constants from exponential fitting or calculatio...

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Main Authors: Patel, Anant B, de Graaf, Robin A, Rothman, Douglas L, Behar, Kevin L, Mason, Graeme F
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879471/
https://ncbi.nlm.nih.gov/pubmed/20125180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.2
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