Characterization of cerebral glutamine uptake from blood in the mouse brain: implications for metabolic modeling of (13)C NMR data

(13)C Nuclear Magnetic Resonance (NMR) studies of rodent and human brain using [1-(13)C]/[1,6-(13)C(2)]glucose as labeled substrate have consistently found a lower enrichment (∼25% to 30%) of glutamine-C4 compared with glutamate-C4 at isotopic steady state. The source of this isotope dilution has no...

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Udgivet i:J Cereb Blood Flow Metab
Main Authors: Bagga, Puneet, Behar, Kevin L, Mason, Graeme F, De Feyter, Henk M, Rothman, Douglas L, Patel, Anant B
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269725/
https://ncbi.nlm.nih.gov/pubmed/25074745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.129
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