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Parkinson's disease and CYP1A2 activity

AIMS: MPTP, a neurotoxin which induces parkinsonism is partially metabolized by the enzyme CYP1A2. Smoking appears to protect against Parkinson's disease (PD) and cigarette smoke induces CYP1A2 activity. Thus, we investigated the hypothesis that idiopathic PD is associated with lower CYP1A2 act...

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Bibliografski detalji
Glavni autori: Forsyth, J T, Grünewald, R A, Rostami-Hodjegan, A, Lennard, M S, Sagar, H J, Tucker, G T
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014998/
https://ncbi.nlm.nih.gov/pubmed/11012552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00259.x
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