The pharmacokinetics and pharmacodynamics of oral dofetilide after twice daily and three times daily dosing

AIMS: The pharmacokinetics and pharmacodynamics of oral dofetilide, a novel, class III antiarrhythmic drug, were assessed during administration either twice or three times daily. METHODS: Dofetilide was administered orally to three groups of healthy subjects in daily doses of 1000 µg (n = 8), 1500 µ...

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Hlavní autoři: Allen, Michael J, Nichols, Donald J, Oliver, Stuart D
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2000
Témata:
Pharmacokinetics/Pharmacodynamics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014985/
https://ncbi.nlm.nih.gov/pubmed/10971309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00243.x
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