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Clinical relevance of genetic polymorphisms in the human CYP2C subfamily
The human CYP2Cs are an important subfamily of P450 enzymes that metabolize approximately 20% of clinically used drugs. There are four members of the subfamily, CYP2C8, CYP2C9, CYP2C19, and CYP2C18. Of these CYP2C8, CYP2C9, and CYP2C19 are of clinical importance. The CYP2Cs also metabolize some endo...
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| 主要作者: | |
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| 格式: | Artigo |
| 語言: | Inglês |
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Blackwell Science Inc
2001
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014584/ https://ncbi.nlm.nih.gov/pubmed/11678778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01499.x |
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