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The transcriptional regulation of the human CYP2C genes

In humans, four members of the CYP2C subfamily (CYP2C8, CYP2C9, CYP2C18, and CYP2C19) metabolize more than 20% of all therapeutic drugs as well as a number of endogenous compounds. The CYP2C enzymes are found predominantly in the liver, where they comprise ∼20% of the total cytochrome P450. A variet...

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Detalhes bibliográficos
Main Authors: Chen, Yuping, Goldstein, Joyce A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808111/
https://ncbi.nlm.nih.gov/pubmed/19702536
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