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Identification of Human CYP2C8 as a Retinoid-Related Orphan Nuclear Receptor Target Gene
Retinoid-related orphan nuclear receptors (RORs) α and γ (NR1F1, -3) are highly expressed in liver, adipose tissue, thymus, and brain and are involved in many physiological processes, such as circadian rhythm and immune function. Enzymes in the cytochrome P450 2C subfamily metabolize many clinically...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2670598/ https://ncbi.nlm.nih.gov/pubmed/19164466 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.148916 |
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