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Human CYP2C8 Is Post-Transcriptionally Regulated by MicroRNAs 103 and 107 in Human Liver

The CYP2C genes are extensively regulated at the transcriptional stage. The present study shows for the first time that CYP2Cs are also regulated post-transcriptionally by microRNAs (miRNAs). By using online search engines, we found potential miRNA response elements (MREs) in the 3′-untranslated reg...

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Библиографические подробности
Главные авторы: Zhang, Shu-Yun, Surapureddi, Sailesh, Coulter, Sherry, Ferguson, Stephen S., Goldstein, Joyce A.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422698/
https://ncbi.nlm.nih.gov/pubmed/22723340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.078386
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