Polymorphisms of CYP2A6 and its practical consequences

CYP2A6 is an hepatic enzyme predominantly with some expression in specialized extrahepatic cell types. The CYP2A6 enzyme has a somewhat restricted active site, accepting only a few xenobiotics as substrates. Interest in CYP2A6 has risen considerably after nicotine and some tobacco specific nitrosami...

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Detalhes bibliográficos
Main Authors: Raunio, Hannu, Rautio, Arja, Gullstén, Harriet, Pelkonen, Olavi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2001
Assuntos:
Review Series Review Series on Pharmacogenomics edited by Prof. M. Pirmohamed
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014580/
https://ncbi.nlm.nih.gov/pubmed/11678779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01500.x
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