A Genetic Polymorphism in Coumarin 7-Hydroxylation: Sequence of the Human CYP2A Gnes and Identification of Variant CYP2A6 Alleles

A group of human cytochrome P450 genes encompassing the CYP2A, CYP2B, and CYP2F subfamilies were cloned and assembled into a 350-kb contig localized on the long arm of chromosome 19. Three complete CYP2A genes—CYP2A6, CYP2A7, and CYP2A13—plus two pseudogenes truncated after exon 5, were identified a...

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Bibliografiske detaljer
Main Authors: Fernandez-Salguero, Pedro, Hoffman, Susan M. G., Cholerton, Suzanne, Mohrenweiser, Harvey, Raunio, Hannu, Rautio, Arja, Pelkonen, Olavi, Huang, Jin-ding, Evans, William E., Idle, Jeffrey R., Gonzalez, Frank J.
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801261/
https://ncbi.nlm.nih.gov/pubmed/7668294
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