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p130(CAS) Is Required for Netrin Signaling and Commissural Axon Guidance
Netrins are an important family of axon guidance cues. Here, we report that netrin-1 induces tyrosine phosphorylation of p130(CAS) (Crk-associated substrate). Our biochemical studies indicate that p130(CAS) is downstream of the Src family kinases and upstream of the small GTPase Rac1 and Cdc42. Inhi...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Society for Neuroscience
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014516/ https://ncbi.nlm.nih.gov/pubmed/17251438 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4616-06.2007 |
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