Effect of the CYP2C19 oxidation polymorphism on fluoxetine metabolism in Chinese healthy subjects

AIMS: The study was designed to investigate whether genetically determined CYP2C19 activity affects the metabolism of fluoxetine in healthy subjects. METHODS: A single oral dose of fluoxetine (40 mg) was administrated successively to 14 healthy young men with high (extensive metabolizers, n =8) and...

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Autores principales: Liu, Zhao-Qian, Cheng, Ze-Neng, Huang, Song-Lin, Chen, Xiao-Ping, Ou-Yang, Dong-Sheng, Jiang, Chang-Hong, Zhou, Hong-Hao
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2001
Materias:
Short Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014504/
https://ncbi.nlm.nih.gov/pubmed/11453896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.0306-5251.2001.01402.x
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