The distribution and gender difference of CYP3A activity in Chinese subjects

AIMS: To investigate the distribution of CYP3A activity in the Chinese population, and to test for gender-related differences in CYP3A activity. METHODS: Using midazolam as a probe drug, CYP3A activity in 202 Chinese healthy subjects (104 men) was measured by plasma 1′-hydroxymidazolam:midazolam (1′...

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Detalhes bibliográficos
Main Authors: Zhu, Bing, Liu, Zhao-Qian, Chen, Guo-Lin, Chen, Xiao-Ping, Ou-Yang, Dong-Sheng, Wang, Lian-Sheng, Huang, Song-Lin, Tan, Zhi-Rong, Zhou, Hong-Hao
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2003
Assuntos:
Drug Disposition
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1884221/
https://ncbi.nlm.nih.gov/pubmed/12630976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2003.01728.x
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