Inhibitory effects of verapamil and diltiazem on simvastatin metabolism in human liver microsomes

AIMS: To determine the effects of verapamil and diltiazem on simvastatin metabolism in human liver microsomes and to compare their inhibitory potencies and CYP3A4 inactivation parameters with those reported previously for mibefradil. METHODS: Simvastatin metabolism was investigated in human liver mi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yeo, Karen Rowland, Yeo, Wilfred W
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2001
Pynciau:
Drug Disposition
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014477/
https://ncbi.nlm.nih.gov/pubmed/11422004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01386.x
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg