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Inhibitory effects of verapamil and diltiazem on simvastatin metabolism in human liver microsomes
AIMS: To determine the effects of verapamil and diltiazem on simvastatin metabolism in human liver microsomes and to compare their inhibitory potencies and CYP3A4 inactivation parameters with those reported previously for mibefradil. METHODS: Simvastatin metabolism was investigated in human liver mi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2001
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014477/ https://ncbi.nlm.nih.gov/pubmed/11422004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01386.x |
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