A single dose of methadone inhibits cytochrome P-4503A activity in healthy volunteers as assessed by the urinary cortisol ratio

AIMS: To examine the effect of a single oral dose of methadone on cytochrome P450 (CYP) 3A activity using the urinary 6β-hydroxycortisol to cortisol ratio (UCR) as a marker of CYP3A activity. METHODS: A single oral dose (0.2 mg kg(−1)) of rac-methadone was administered to eight healthy female volunt...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Boulton, David W, Arnaud, Philippe, DeVane, C Lindsay
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Blackwell Science Inc 2001
Aiheet:
Short Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014462/
https://ncbi.nlm.nih.gov/pubmed/11318772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2001.01360.x
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia