Pharmacokinetics of SDZ RAD and cyclosporin including their metabolites in seven kidney graft patients after the first dose of SDZ RAD

AIMS: The aim of the study was to investigate the pharmacokinetics and metabolism of the new immunosuppressant SDZ RAD during concomitant therapy with cyclosporin in stable renal transplant patients. Furthermore, we studied the influence of SDZ RAD on the pharmacokinetics of cyclosporin at steady st...

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Autors principals: Kirchner, Gabriele I, Winkler, Michael, Mueller, Lueke, Vidal, Christian, Jacobsen, Wolfgang, Franzke, Anke, Wagner, Siegfried, Blick, Stefan, Manns, Michael P, Sewing, Karl-Friedrich
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2000
Matèries:
Pharmacokinetics/Pharmacodynamics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014408/
https://ncbi.nlm.nih.gov/pubmed/11069439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00293.x
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