Pharmacokinetics of SDZ RAD and cyclosporin including their metabolites in seven kidney graft patients after the first dose of SDZ RAD

AIMS: The aim of the study was to investigate the pharmacokinetics and metabolism of the new immunosuppressant SDZ RAD during concomitant therapy with cyclosporin in stable renal transplant patients. Furthermore, we studied the influence of SDZ RAD on the pharmacokinetics of cyclosporin at steady st...

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Bibliographic Details
Main Authors: Kirchner, Gabriele I, Winkler, Michael, Mueller, Lueke, Vidal, Christian, Jacobsen, Wolfgang, Franzke, Anke, Wagner, Siegfried, Blick, Stefan, Manns, Michael P, Sewing, Karl-Friedrich
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2000
Subjects:
Pharmacokinetics/Pharmacodynamics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014408/
https://ncbi.nlm.nih.gov/pubmed/11069439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00293.x
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