Cargando...

Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain

1. Clinical studies have shown enhancement of cyclosporine toxicity when co-administered with the immunosuppressant sirolimus. We evaluated the biochemical mechanisms underlying the sirolimus/cyclosporine interaction on rat brain metabolism using magnetic resonance spectroscopy (MRS) and compared th...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Serkova, Natalie, Jacobsen, Wolfgang, Niemann, Claus U, Litt, Lawrence, Benet, Leslie Z, Leibfritz, Dieter, Christians, Uwe
Formato: Artigo
Lenguaje:Inglês
Publicado: 2001
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572850/
https://ncbi.nlm.nih.gov/pubmed/11454661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704142
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!