Role of lipoproteins in the plasma binding of SDZ PSC 833, a novel multidrug resistance-reversing cyclosporin

AIMS: The plasma binding of the cyclosporin D analogue SDZ PSC 833 was investigated in vitro. METHODS: The plasma total binding constant (corresponding to the bound-to-free concentration or binding ratio) was determined at 37° C by the erythrocyte partitioning technique on plasma samples from three...

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Detalhes bibliográficos
Main Authors: Simon, Nicolas, Dailly, Eric, Combes, Olivier, Malaurie, Emmanuelle, Lemaire, Michel, Tillement, Jean-Paul, Urien, Saïk
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873350/
https://ncbi.nlm.nih.gov/pubmed/9491834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00663.x
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