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Pharmacokinetics of dihydrocodeine and its active metabolite after single and multiple oral dosing
AIMS: The pharmacokinetics of dihydrocodeine (DHC) and its active metabolite dihydromorphine (DHM) were assessed after a single oral dose of DHC and after increasing doses of DHC at steady-state. METHODS: Twelve healthy male volunteers (18–45 years, CYP2D6 extensive metabolizers (EMs), MR<1 took...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Science Inc
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2014322/ https://ncbi.nlm.nih.gov/pubmed/10510141 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00042.x |
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