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Diclofenac does not interact with codeine metabolism in vivo: A study in healthy volunteers
BACKGROUND: Previously, we have demonstrated a marked inhibition of codeine glucuronidation by diclofenac in human liver tissue homogenate. We therefore aimed to investigate whether diclofenac inhibits glucuronidation of codeine also in vivo in healthy volunteers. METHODS: In a randomised, placebo-c...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC101395/ https://ncbi.nlm.nih.gov/pubmed/11943073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6904-2-2 |
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