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Pretreatment with simvastatin reduces myocardial no-reflow by opening mitochondrial K(ATP) channel

BACKGROUND AND PURPOSE: Simvastatin, a cholesterol-lowering agent, can protect against endothelial dysfunction. However, the effects of simvastatin treatment on the restoration of blood flow to ischemic myocardium are not known. This study sought to assess such effects of simvastatin on an experimen...

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Detalhes bibliográficos
Main Authors: Zhao, J-L, Yang, Y-J, Cui, C-J, you, S-J, Gao, R-L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014278/
https://ncbi.nlm.nih.gov/pubmed/16921391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706862
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