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Opening of the MitoK(ATP) Channel and Decoupling of Mitochondrial Complex II and III Contribute to the Suppression of Myocardial Reperfusion Hyperoxygenation
Diazoxide, a mitochondrial ATP-sensitive potassium (mitoK(ATP)) channel opener, protects the heart from ischemia-reperfusion injury. Diazoxide also inhibits mitochondrial complex II-dependent respiration in addition to its preconditioning effect. However, there are no prior studies of the role of di...
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Auteurs principaux: | , , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
2009
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3738814/ https://ncbi.nlm.nih.gov/pubmed/19851835 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-009-0283-2 |
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