CYP2D6 polymorphism in a Gabonese population: contribution of the CYP2D6*2and CYP2D6*17alleles to the high prevalence of the intermediate metabolic phenotype

AIMS: To determine the molecular basis of the intermediate extensive metaboliser (EM) CYP2D6 phenotype in healthy Gabonese subjects. METHODS: The CYP2D6 phenotype of 154 healthy Gabonese subjects was assessed by giving the subject a single dose of 30 mg dextromethorphan, and collecting their urine f...

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Detalhes bibliográficos
Main Authors: Panserat, S, Sica, L, Gérard, N, Mathieu, H, Jacqz-Aigrain, E, Krishnamoorthy, R
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1999
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014206/
https://ncbi.nlm.nih.gov/pubmed/10073750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1999.00861.x
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