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Inhibition of Cyclooxygenases by Dipyrone

BACKGROUND AND PURPOSE: Dipyrone is a potent analgesic drug that has been demonstrated to inhibit cyclooxygenase (COX). In contrast to classical COX-inhibitors, such as aspirin-like drugs, dipyrone has no anti-inflammatory effect and a low gastrointestinal toxicity, indicating a different mode of ac...

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Detalhes bibliográficos
Main Authors: Pierre, S C, Schmidt, R, Brenneis, C, Michaelis, M, Geisslinger, G, Scholich, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013970/
https://ncbi.nlm.nih.gov/pubmed/17435797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707239
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