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PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate

PAM (Protein Associated with Myc) is an almost ubiquitously expressed protein that is one of the most potent inhibitors of adenylyl cyclase activity known so far. Here we show that PAM is localized at the endoplasmic reticulum in HeLa cells and that upon serum treatment PAM is recruited to the plasm...

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Autori principali: Pierre, Sandra C, Häusler, Julia, Birod, Kerstin, Geisslinger, Gerd, Scholich, Klaus
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC514936/
https://ncbi.nlm.nih.gov/pubmed/15257286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600321
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