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PAM mediates sustained inhibition of cAMP signaling by sphingosine-1-phosphate

PAM (Protein Associated with Myc) is an almost ubiquitously expressed protein that is one of the most potent inhibitors of adenylyl cyclase activity known so far. Here we show that PAM is localized at the endoplasmic reticulum in HeLa cells and that upon serum treatment PAM is recruited to the plasm...

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Detalhes bibliográficos
Main Authors: Pierre, Sandra C, Häusler, Julia, Birod, Kerstin, Geisslinger, Gerd, Scholich, Klaus
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC514936/
https://ncbi.nlm.nih.gov/pubmed/15257286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600321
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