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Somatostatin inhibits colon cancer cell growth through cyclooxygenase-2 downregulation
BACKGROUND AND PURPOSE: Cyclooxygenase-2 (COX-2) is expressed in colonic neoplasms, where it supports cell proliferation via prostaglandin E(2) (PGE(2)) production. This study investigated the effects of somatostatin-14 on COX-2 expression, PGE(2) production and proliferation in colon cancer cells....
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538699/ https://ncbi.nlm.nih.gov/pubmed/18587421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.268 |
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