Somatostatin inhibits colon cancer cell growth through cyclooxygenase-2 downregulation

BACKGROUND AND PURPOSE: Cyclooxygenase-2 (COX-2) is expressed in colonic neoplasms, where it supports cell proliferation via prostaglandin E(2) (PGE(2)) production. This study investigated the effects of somatostatin-14 on COX-2 expression, PGE(2) production and proliferation in colon cancer cells....

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Colucci, R, Blandizzi, C, Ghisu, N, Florio, T, Del Tacca, M
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2008
Sujets:
Research Papers
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538699/
https://ncbi.nlm.nih.gov/pubmed/18587421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.268
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