Gastrin promotes human colon cancer cell growth via CCK-2 receptor-mediated cyclooxygenase-2 induction and prostaglandin E(2) production

1. The present study investigates the effects of gastrin-17 on human colon cancer HT-29 cells to examine whether gastrin receptor (CCK-2), cyclooxygenase (COX-1, COX-2) isoforms and prostaglandin receptor pathways interact to control cell growth. 2. Reverse transcription (RT)–polymerase chain reacti...

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Autors principals: Colucci, Rocchina, Blandizzi, Corrado, Tanini, Marzia, Vassalle, Cristina, Breschi, Maria Cristina, Tacca, Mario Del
Format: Artigo
Idioma:Inglês
Publicat: 2005
Matèries:
Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1576011/
https://ncbi.nlm.nih.gov/pubmed/15655524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706053
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