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Analgesic actions of N-arachidonoyl-serotonin, a fatty acid amide hydrolase inhibitor with antagonistic activity at vanilloid TRPV1 receptors

BACKGROUND AND PURPOSE: N-arachidonoyl-serotonin (AA-5-HT) is an inhibitor of fatty acid amide hydrolase (FAAH)-catalysed hydrolysis of the endocannabinoid/ endovanilloid compound, anandamide (AEA). We investigated if AA-5-HT antagonizes the transient receptor potential vanilloid-1 (TRPV1) channel a...

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Bibliografiske detaljer
Main Authors: Maione, S, De Petrocellis, L, de Novellis, V, Moriello, A Schiano, Petrosino, S, Palazzo, E, Rossi, F Sca, Woodward, D F, Di Marzo, V
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013858/
https://ncbi.nlm.nih.gov/pubmed/17279090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707145
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