تحميل...
Mixed-backbone oligonucleotides as second generation antisense oligonucleotides: In vitro and in vivo studies
Antisense oligonucleotides are being evaluated in clinical trials as novel therapeutic agents. To further improve the properties of antisense oligonucleotides, we have designed mixed-backbone oligonucleotides (MBOs) that contain phosphorothioate segments at the 3′ and 5′ ends and have a modified oli...
محفوظ في:
| المؤلفون الرئيسيون: | , , , , , , , , |
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| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
The National Academy of Sciences of the USA
1997
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC20138/ https://ncbi.nlm.nih.gov/pubmed/9122245 |
| الوسوم: |
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