Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A

Protein kinase A type I plays a key role in neoplastic transformation, conveying mitogenic signals of different growth factors and oncogenes. Inhibition of protein kinase A type I by antisense oligonucleotides targeting its RIα regulatory subunit results in cancer cell growth inhibition in vitro and...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Tortora, Giampaolo, Caputo, Rosa, Damiano, Vincenzo, Bianco, Roberto, Pepe, Stefano, Bianco, A. Raffaele, Jiang, Zhiwei, Agrawal, Sudhir, Ciardiello, Fortunato
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25047/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9356493/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.23.12586
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