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Synergistic inhibition of human cancer cell growth by cytotoxic drugs and mixed backbone antisense oligonucleotide targeting protein kinase A

Protein kinase A type I plays a key role in neoplastic transformation, conveying mitogenic signals of different growth factors and oncogenes. Inhibition of protein kinase A type I by antisense oligonucleotides targeting its RIα regulatory subunit results in cancer cell growth inhibition in vitro and...

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Bibliografiske detaljer
Main Authors: Tortora, Giampaolo, Caputo, Rosa, Damiano, Vincenzo, Bianco, Roberto, Pepe, Stefano, Bianco, A. Raffaele, Jiang, Zhiwei, Agrawal, Sudhir, Ciardiello, Fortunato
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences of the USA 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC25047/
https://ncbi.nlm.nih.gov/pubmed/9356493
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