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Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia

BACKGROUND AND AIMS: Lymphocytes populate the livers of infants with biliary atresia, but it is unknown whether neonatal lymphocytes regulate pathogenesis of disease. Here, we investigate this question by examining the role of T lymphocytes in the destruction of extrahepatic bile ducts of neonatal m...

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Autors principals: Shivakumar, Pranavkumar, Sabla, Gregg, Mohanty, Sujit, McNeal, Monica, Ward, Richard, Stringer, Keith, Caldwell, Charles, Chougnet, Claire, Bezerra, Jorge A.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2013308/
https://ncbi.nlm.nih.gov/pubmed/17631148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.04.031
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