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Cyclic AMP Signaling Pathway Modulates Susceptibility of Candida Species and Saccharomyces cerevisiae to Antifungal Azoles and Other Sterol Biosynthesis Inhibitors

Azoles are widely used antifungals; however, their efficacy is compromised by fungistatic activity and selection of resistant strains during treatment. Recent studies demonstrated roles for the protein kinase C and calcium signaling pathways in modulating azole activity. Here we explored a role for...

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Detalhes bibliográficos
Main Authors: Jain, Pooja, Akula, Indira, Edlind, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC201163/
https://ncbi.nlm.nih.gov/pubmed/14506030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.10.3195-3201.2003
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