Cyclic AMP Signaling Pathway Modulates Susceptibility of Candida Species and Saccharomyces cerevisiae to Antifungal Azoles and Other Sterol Biosynthesis Inhibitors

Azoles are widely used antifungals; however, their efficacy is compromised by fungistatic activity and selection of resistant strains during treatment. Recent studies demonstrated roles for the protein kinase C and calcium signaling pathways in modulating azole activity. Here we explored a role for...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Jain, Pooja, Akula, Indira, Edlind, Thomas
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Mechanisms of Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC201163/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14506030/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.47.10.3195-3201.2003
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