The radiosensitizer Ro 03-8799 and the concentrations which may be achieved in human tumours: a preliminary study.

A new hypoxic cell radiosensitizer, Ro 03-8799, has been administered i.v. to 2 normal and 6 patient volunteers. Generally in non-necrotic tumours the concentrations obtained were 3 times greater than in plasma sampled at the same time. These observations added to the reports concerning toxicology i...

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Main Authors: Saunders, M. I., Dische, S., Fermont, D., Bishop, A., Lenox-Smith, I., Allen, J. G., Malcolm, S. L.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 1982
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2011152/
https://ncbi.nlm.nih.gov/pubmed/7171452
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