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Effect of the nitroimidazole Ro 03-8799 on the activity of chemotherapeutic agents against a murine tumour in vivo.

The effect of the 2-nitroimidazole Ro 03-8799 (8799) on the activity of 11 chemotherapeutic agents against the anaplastic MT tumour in mice has been determined by soft agar cloning. The 8799, whilst producing little cytotoxicity by itself, potentiated the cytotoxic actions of the alkylating agents m...

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Détails bibliographiques
Auteurs principaux: Sheldon, P. W., Gibson, P.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 1984
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976734/
https://ncbi.nlm.nih.gov/pubmed/6704303
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